The small GTPase Rap1 is an immediate downstream target for Hoxb4 transcriptional regulation
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چکیده
منابع مشابه
The small GTPase Rap1 is an immediate downstream target for Hoxb4 transcriptional regulation
The Hox genes are a family of homeodomain-containing transcription factors which determine anteroposterior identity early on in development. Although a lot is now known about their regulation and function, very little is known of their effector (downstream target) genes. Here we show that the small GTPase Rap1 is a direct, negatively regulated target of Hoxb4 and is excluded from Hoxb4 expressi...
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Istituto di Endocrinologia ed Oncologia Sperimentale del CNR ”G.Salvatore”, c/o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Universita’ Federico II, 80131 Naples, Italy (VDF, MC, GD, AMC, AF, RMM, MS). Endocrinology and Metabolism Division, UCLA School of Medicine, Los Angeles, California (JMH); and Instituto de Biologia Molecular y Celular del Cancer, Centro de Investigacion d...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 2002
ISSN: 0925-4773
DOI: 10.1016/s0925-4773(02)00047-3